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Dextromethorphan HBR
Pharmaceutical Grade | Manufacturer & Exporter from India
Dextromethorphan HBR API – Pharmaceutical Grade | Manufacturer & Exporter from India
Dextromethorphan Hydrobromide (HBR) is a high-quality Active Pharmaceutical Ingredient (API) widely recognized for its efficacy as a centrally acting antitussive (cough suppressant). Shabbir Chemicals is a trusted manufacturer and exporter, providing premium-grade Dextromethorphan HBr to the global pharmaceutical industry, ensuring strict adherence to international standards.
Product Overview
- Synonyms: (+)-3-Methoxy-17-methyl-9α,13α,14α-morphinan hydrobromide monohydrate
- CAS No: 6700-34-1 (Monohydrate) / 125-69-9 (Anhydrous)
- Code: DXM-HBR
- Grade: BP / USP / EP / IP
- Mol. Formula: C₁₈H₂₅NO·HBr·H₂O
- Mol. Weight: 370.32 g/mol
- Purity (Assay): 99.0% – 102.0% (on anhydrous basis)
Description
Dextromethorphan Hydrobromide appears as a white or almost white crystalline powder. It is an odourless, non-opioid derivative of morphine used primarily to provide temporary relief from dry, non-productive coughs caused by minor throat and bronchial irritation. Unlike opioid antitussives, it does not possess analgesic or addictive properties at therapeutic doses, making it a staple in over-the-counter (OTC) cough and cold formulations.
Applications
- Antitussive Medications: The primary active ingredient in cough syrups, lozenges, and oral suspensions.
- Combination Drugs: Frequently formulated alongside antihistamines (e.g., Chlorpheniramine Maleate), decongestants (e.g., Phenylephrine), and expectorants (e.g., Guaifenesin) for multi-symptom cold relief.
- Neurological Research: Increasingly studied for its potential in treating various neuropsychiatric disorders due to its action on NMDA receptors.
Technical Specifications
| Test Item | Specification |
|---|---|
| Appearance | White or almost white crystalline powder |
| Solubility | Freely soluble in alcohol and chloroform; sparingly soluble in water |
| Melting Point | 122°C to 126°C |
| Specific Optical Rotation | +28.0° to +30.0° |
| pH (1% solution) | 5.2 to 6.5 |
| Water Content | 3.5% to 5.5% |
| Residue on Ignition | Not more than 0.1% |
| Heavy Metals | ≤ 20 ppm |
Safety & Hazard Information
- Signal Word: Warning
- Hazard Statements: * H302: Harmful if swallowed.
- H336: May cause drowsiness or dizziness.
- Precautionary Statements:
- P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
- P264: Wash hands thoroughly after handling.
- P301 + P312: IF SWALLOWED: Call a POISON CENTER if you feel unwell.
- Personal Protective Equipment (PPE): Safety goggles, gloves, and dust masks are recommended during bulk handling.
Packaging & Logistics
- Standard Packaging: 25 kg HDPE Drums with inner double LDPE liners.
- Storage: Store in a cool, dry place. Keep container tightly closed and protected from light.
- Shipping: Available for export to Gulf countries, SE Asia, Europe, and Latin America.
- MSDS / COA: Available upon request.
Why Choose Shabbir Chemicals
As a leading Dextromethorphan HBr Manufacturer, we leverage decades of expertise in pharmaceutical chemistry to deliver precision and safety. Our manufacturing facility follows cGMP guidelines, ensuring that every batch meets the rigorous purity requirements of our global clientele.